Jitske Jansen

This study identifies a novel mechanism in myelofibrosis where a single mutation drives both bone formation and resorption, revealing THBS1 as a therapeutic target.

PHLOWER infers complex differentiation trees from multi-modal single-cell data using Hodge Laplacian decomposition, showing effectiveness in kidney organoid data.

This study uses human pluripotent stem cell-derived kidney organoids to model nephrotic syndrome, showing they can replicate podocyte injury and respond to genetic correction.

This study shows cocaine increases extracellular dopamine and serotonin by depleting storage vesicles in the rat nucleus accumbens, with individual differences in vesicular release affecting behavior and drug intake.