Cédric Raoul

This study shows LINGO1 is upregulated in SOD1(G93A) mice during ALS progression and early oligodendrogenesis, with miR-138 downregulation, suggesting potential therapeutic targets for ALS.

This study shows that Fn14-depletion improves survival and muscle pathology in SOD1G93A ALS mice, but only when combined with exercise.

This study shows that FGF4 reduces ALS astrocyte reactivity but fails to protect motor neurons in a mouse model, while TNF exacerbates astrocyte dysfunction.

This study shows Fas activation induces both death and axonal growth in motoneurons, with distinct molecular pathways involved in each response.