Author

Gareth Hazell

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1 Pathology· 1

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Joseph M. HoolachaniD· 2 shared Matthew J. A. WoodiD· 2 shared Mélissa BowermaniD· 2 shared Nina AhlskogiD· 2 shared Amarjit BhomraiD· 1 shared Anna J. KordalaiD· 1 shared Caleb WebberiD· 1 shared Cédric RaouliD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPathology

Joseph M. HoolachanORCID

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2 papers

Recent·Most cited

Exercise and disease state influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model

Gareth Hazell, Eve McCallion, Nina Ahlskog, Emma R Sutton, Magnus Okoh, Emad I. Shaqoura, Joseph M. Hoolachan, Taylor Scaife, Sara Iqbal, Amarjit Bhomra, Anna J. Kordala, Frédérique Scamps, Cédric Raoul, Matthew J. A. Wood, Mélissa Bowerman

This study shows that Fn14-depletion improves survival and muscle pathology in SOD1G93A ALS mice, but only when combined with exercise.

Skeletal Muscle · Oct 14, 2024Peer-reviewedPathology

Combining multi-omics and drug perturbation profiles to identify novel treatments that improve disease phenotypes in spinal muscular atrophy

Katharina E. Meijboom, Viola Volpato, Jimena Monzón‐Sandoval, Joseph M. Hoolachan, Suzan M. Hammond, Frank Abendroth, Olivier G. de Jong, Gareth Hazell, Nina Ahlskog, Matthew J. A. Wood, Caleb Webber, Mélissa Bowerman

This study identifies novel drug treatments for spinal muscular atrophy by integrating multi-omics data and drug perturbation profiles, showing harmine improves disease phenotypes in models.

bioRxiv · Dec 17, 2019 · PreprintNeuroscience