Author

Natasha C. Chang

McGill UniversityORCID 0000-0003-0589-9660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Jules A GranetiD· 2 shared Rebecca RobertsoniD· 2 shared Alessio A Cusmano· 1 shared Cordell A. VanGendereniD· 1 shared Ishtiaque HossainiD· 1 shared Jo Anne StrattoniD· 1 shared John SaberiD· 1 shared Michael A. RudnickiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Jules A GranetORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 20, 2026

Phosphorylation of CARM1 at Ser572 preserves muscle stem cell self-renewal by restricting premature myogenic commitment

Cordell A. VanGenderen, Rebecca Robertson, Jules A Granet…·Natasha C. Chang

This study shows that phosphorylation of CARM1 at Ser572 is essential for maintaining muscle stem cell self-renewal by preventing premature myogenic commitment.

DOI 10.64898/2026.10.17.759715

mouseexperimental assay

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Cell BiologyCell Death and DiseasePeer-reviewedJun 5, 2025

Muscle stem cells in Duchenne muscular dystrophy exhibit molecular impairments and altered cell fate trajectories impacting regenerative capacity

Jules A Granet, Rebecca Robertson, Alessio A Cusmano…·Natasha C. Chang

This study uses scRNA-seq to show that DMD satellite cells have molecular impairments and altered differentiation trajectories, leading to reduced regenerative capacity, with autophagy induction potentially rescuing differentiation.

28 citationstop 2%

mousescRNA-seq

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