Author

Ishtiaque Hossain

McGill UniversityORCID 0000-0002-4494-0366Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

William A. PastoriD· 3 shared Deepak SainiiD· 2 shared Jacinthe Sirois· 2 shared Adda-Lee Graham-PaquiniD· 1 shared Christopher MoraesiD· 1 shared Cordell A. VanGendereniD· 1 shared Guillaume BourqueiD· 1 shared John SaberiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMolecular Biology

William A. PastorORCID

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3 papers

Recent·Most cited

Phosphorylation of CARM1 at Ser572 preserves muscle stem cell self-renewal by restricting premature myogenic commitment

Cordell A. VanGenderen, Rebecca Robertson, Jules A Granet, Ishtiaque Hossain, Ronit Mohapatra, John Saber, Michael A. Rudnicki, William A. Pastor, Natasha C. Chang

This study shows that phosphorylation of CARM1 at Ser572 is essential for maintaining muscle stem cell self-renewal by preventing premature myogenic commitment.

bioRxiv · Oct 20, 2026 · PreprintCell Biology

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development

Adda-Lee Graham-Paquin, Deepak Saini, Jacinthe Sirois, Ishtiaque Hossain, Megan S. Katz, Qinwei Kim-Wee Zhuang, Sin Young Kwon, Yojiro Yamanaka, Guillaume Bourque, Maxime Bouchard, William A. Pastor

This study identifies ZMYM2 as essential for DNA methylation and silencing of germline genes and active transposons in embryonic development, revealing its role in maintaining genomic stability.

Nucleic Acids Research · Jun 10, 2023Peer-reviewedMolecular Biology

The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells

Nathália Azevedo Portilho, Deepak Saini, Ishtiaque Hossain, Jacinthe Sirois, Christopher Moraes, William A. Pastor

This study compares the demethylation efficacy and toxicity of GSK-3484862 and 5-azanucleosides in murine embryonic stem cells, finding GSK-3484862 induces more effective demethylation with less toxicity.

Epigenetics & Chromatin · Dec 1, 2021Peer-reviewedMolecular Biology