Filip Ježek

This paper develops a multiscale computational model to simulate cardiopulmonary effects of postnatal hyperoxia in rats, showing agreement with experimental data and capturing abnormalities seen in preterm humans.

This paper develops a kinetic model to interpret mant-ATP fluorescence decay in myosin SRX state measurements, showing that decay phases result from label redistribution, not equilibrium states.

This paper develops a theoretical model to explain power-law stress relaxation and calcium-dependent passive mechanics in cardiac muscle by simulating domain unfolding in titin.

This study shows that Ca2+ increases cardiac muscle viscoelasticity independently of active force development, with a >6-fold increase in apparent viscoelasticity at higher Ca2+ levels.