Author

Eva Hrubá

Masaryk UniversityORCID 0000-0003-0651-059XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Tomáš BártaiD· 3 shared Canan CelikeriD· 2 shared Francisco Molina GambiniD· 2 shared Alejandro GarantoiD· 1 shared Birthe DorgauiD· 1 shared David StaněkiD· 1 shared Edwin van OosteniD· 1 shared Eleni BeliiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

Tomáš BártaORCID

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3 papers

Recent·Most cited

Photostimulation Improves Maturation of Human Photoreceptors

Canan Celiker, Eva Hrubá, Konstantina Kyriakou, Birthe Dorgau, Francisco Molina Gambin, Kamila Weissová, Edwin van Oosten, Lucie Englmaier, Naděžda Vaškovicová, Michael A. Savage, Gerrit Hilgen, Evelyne Sernagor, Alejandro Garanto, Majlinda Lako, Tomáš Bárta

This study shows that rhythmic light flicker improves photoreceptor maturation in human retinal organoids by enhancing structural development, transcriptional transition, and functional connectivity.

Nature Communications · Aug 12, 2026Peer-reviewedCell Biology

PRPF8-associated retinitis pigmentosa variant induces human neural retina-autonomous photoreceptor defects

Felix Zimmann, Poulami Banik, Jan Kubovčiak, Mathys Delattre, Prasoon Kumar Thakur, Martin Čapek, Michal Kolář, Eva Hrubá, Robert Dobrovolný, Zuzana Cvačková, Tomáš Bárta, David Staněk

This study shows that the PRPF8-Y2334N variant causes photoreceptor defects in human neural retina cells without affecting the retinal pigment epithelium.

Scientific Reports · Feb 23, 2026Peer-reviewedCell Biology

Unveiling the Cellular and Molecular Mechanisms of Diabetic Retinopathy with Human Retinal Organoids

Lada Polesovska, Simona Trmacova, Canan Celiker, Eva Hrubá, Francisco Molina Gambin, Václav Chochola, Veronika Matušková, Eleni Beli, Tomáš Bárta

This study uses human retinal organoids to investigate hyperglycaemia's effects on retinal development, finding disruptions in photoreceptor maturation and glial activation.

Cell Death and Disease · Dec 19, 2025Peer-reviewedCell Biology