Author

Xiaodun Yang

University of PennsylvaniaORCID 0000-0001-9253-9449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anastasia GoloviniD· 1 shared Appakalai N. BalamuruganiD· 1 shared Changhong LiiD· 1 shared Chen Lu HuangiD· 1 shared Chen WengiD· 1 shared Christopher V.E. WrightiD· 1 shared Diana E. StanescuiD· 1 shared Doris A. StoffersiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Anastasia GolovinORCID

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2 papers

Recent·Most cited

PDX1 directs a core developmentally and evolutionarily conserved gene program in the pancreatic islet

Xiaodun Yang, Jeffrey C. Raum, Junil Kim, Reynold Yu, Juxiang Yang, Gabriella Rice, Changhong Li, Kyoung‐Jae Won, Doris A. Stoffers, Diana E. Stanescu

The paper identifies a core set of developmentally and evolutionarily conserved PDX1-bound genes in mouse and human pancreas development, showing stable PDX1 binding across ages with context-dependent regulatory roles.

bioRxiv · Feb 28, 2021 · PreprintDevelopmental Biology

Myt Transcription Factors prevent stress-response gene over-activation to enable postnatal pancreatic β cell proliferation and function

Ruiying Hu, Emily M. Walker, Yanwen Xu, Chen Lu Huang, Chen Weng, Gillian E. Erickson, Anastasia Golovin, Xiaodun Yang, Marcella Brissova, Appakalai N. Balamurugan, Christopher V.E. Wright, Yan Li, Roland W. Stein, Guoqiang Gu

This study shows that Myt transcription factors prevent over-activation of stress-response genes in pancreatic β cells, maintaining their function and survival.

bioRxiv · Sep 18, 2019 · PreprintDevelopmental Biology