Developmental BiologybioRxivPreprint
Chemically-defined induction of a primitive endoderm and epiblast-like niche supports post-implantation progression from blastoids.
Erik Vrij, Yvonne Scholte op Reimer, Javier Frias-Aldeguer…·Nicolas C. Rivron
The paper shows that chemically-defined conditions and signaling molecules can generate primitive endoderm-like cells and support post-implantation-like epiblast development in vitro.