Ryann M. Perez

This paper introduces hint token learning to improve protein language models on mutational datasets through three case studies, showing better performance than traditional fine-tuning.

The paper uses structural and chemical biology methods to show EX-6 binds selectively to α-synuclein fibrils in MSA tissue, with a 10-fold preference over PD tissue.

This study investigates how thioamide substitutions in SpyTag affect ligation kinetics with SpyCatcher, showing both faster and slower complex formation depending on substitution position.