Author

C.A. Bingman

University of Wisconsin–MadisonORCID 0000-0002-3073-5089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Biochemistry· 1 Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Marvin WickensiD· 3 shared Judith E. KimbleiD· 2 shared Scott Takeo AokiiD· 2 shared Aman Prasad· 1 shared Cristian A. EscobariD· 1 shared David S. RobertsiD· 1 shared Deane F. MosheriD· 1 shared Douglas F. PorteriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersDevelopmental Biology

Marvin WickensORCID

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5 papers

Recent·Most cited

Rational design of a foldon-derived heterotrimer guided by quantitative native mass spectrometry

Xinyu Liu, David S. Roberts, C.A. Bingman, Song Jin, Ying Ge

This study designs a stable heterotrimeric protein complex using rational design and native mass spectrometry, validated by X-ray crystallography.

Journal of the American Chemical Society · Jun 28, 2025Peer-reviewedBiochemistry

In situ crystalline structure of the Eosinophil major basic protein-1

Jie E Yang, Joshua M. Mitchell, C.A. Bingman, Deane F. Mosher, Elizabeth Wright

This study determines the in-situ crystalline structure of MBP-1 in eosinophil secretory granules and shows activation-dependent crystal expansion and extrusion.

bioRxiv · Oct 9, 2024 · PreprintBiophysics

An Atypical RNA Quadruplex Marks RNAs as Vectors for Gene Silencing

Saeed Roschdi, Jenny Jiacheng Yan, Yuichiro Nomura, Cristian A. Escobar, Riley J. Petersen, C.A. Bingman, Marco Tonelli, Rahul Vivek, Eric Montemayor, Marvin Wickens, Scott G. Kennedy, Samuel E. Butcher

The paper identifies a novel RNA quadruplex structure, the pUG fold, that drives gene silencing in C. elegans and is present in human non-coding RNAs.

Nature Structural & Molecular Biology · Nov 1, 2022Peer-reviewedMolecular Biology

Liquid droplet germ granules require assembly and localized regulators for mRNA repression

Scott Takeo Aoki, Tina R. Lynch, Sarah L. Crittenden, C.A. Bingman, Marvin Wickens, Judith E. Kimble

The paper investigates how PGL dimerization is essential for P-granule assembly and mRNA repression in nematodes, identifying WAGO-1 as a key regulator.

Nature Communications · Feb 12, 2021Peer-reviewedDevelopmental Biology

An RNA binding polymer specifies nematode sperm fate

Scott Takeo Aoki, Douglas F. Porter, Aman Prasad, Marvin Wickens, C.A. Bingman, Judith E. Kimble

The paper identifies FOG-3 as a Tob/BTG protein that forms polymers to regulate sperm fate in nematodes through RNA binding.

Cell Reports · Jun 1, 2018Peer-reviewedDevelopmental Biology