NeurosciencebioRxivPreprint
Complementary Structural and Chemical Biology Methods Reveal the Basis for Selective Radioligand Binding to α-Synuclein in MSA Tissue
Juan C Sanchez, Ryann M. Perez, Dinahlee Saturnino Guarino…·Elizabeth Wright
The paper uses structural and chemical biology methods to show EX-6 binds selectively to α-synuclein fibrils in MSA tissue, with a 10-fold preference over PD tissue.
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