Srividya Tamirisa

The paper investigates how chromosome pairing affects 3D chromatin organization in Drosophila, showing it reinforces intrachromosomal interactions but not compartmental organization.

The paper confirms a compensatory mechanism involving maternal dH1 expression in Drosophila embryos lacking dBigH1, but shows this mechanism is not activated in bigH1100 mutants.

WEADE provides a web tool for integrated enrichment analysis and data exploration of genomic datasets, enabling comparison of experiments and visualization of functional interactions.

The paper identifies key regulatory mechanisms in Drosophila male stem cells and provides a public dataset and tool for analyzing stem cell gene networks.