Gregor Bieri

This study shows APOE4 affects female bone quality more than male bone, without structural changes, by disrupting osteocyte function.

The paper shows that reversing age-related changes in oligodendrocyte-derived extracellular matrix improves cognition in aged mice.

Activating the Gαq pathway in aged worms and mice improves memory and cognitive function, demonstrating conservation across species.

This study shows that LRRK2 modifies α-syn aggregation and spread in both mouse and human models, suggesting potential therapeutic targets for Parkinson's disease.

Genome-wide CRISPR-Cas9 screens in human cells reveal mechanisms and targets for ALS-associated C9orf72 dipeptide repeat protein toxicity.