Author

Marina R. Alexander

Commonwealth Scientific and Industrial Research OrganisationORCID 0000-0003-0745-7903Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alicia C. GrealyiD· 2 shared Clare E. HolleleyiD· 2 shared Erin E. HahniD· 2 shared Jiri Stiller· 2 shared Alexandra L. McAllaniD· 1 shared Arwaf S. AlharbiiD· 1 shared Ben CorryiD· 1 shared Cameron R. StewartiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenomics

Alicia C. GrealyORCID

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3 papers

Recent·Most cited

ImmunologyNature ImmunologyPeer-reviewedFeb 10, 2026

2'-O-Methyl-guanosine 3-base RNA fragments mediate essential natural TLR7/8 antagonism

Arwaf S. Alharbi, Sunil Sapkota, Zhikuan Zhang…·Michael Paul Gantier

The paper identifies 2'-O-methyl-guanosine RNA fragments as natural antagonists of TLR7/8, preventing auto-immunity by inhibiting TLR signaling.

27 citationstop 1%

humanexperimental assay

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GenomicsbioRxivPreprintJul 26, 2023

Century-old chromatin architecture preserved with formaldehyde

Erin E. Hahn, Jiri Stiller, Marina R. Alexander…·Clare E. Holleley

This paper develops a method to analyze chromatin architecture in formaldehyde-preserved specimens up to 117 years old, revealing preserved patterns and new insights into chromatin dynamics.

3 citations

ChIP-seqexperimental assay

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GenomicsMolecular Ecology ResourcesPeer-reviewedSep 22, 2021

Unlocking inaccessible historical genomes preserved in formalin

Erin E. Hahn, Marina R. Alexander, Alicia C. Grealy…·Clare E. Holleley

This study improves genomic analysis of formalin-preserved specimens by refining processing methods and identifying predictors of sequencing success, enabling complete mitochondrial genomes and up to 3X nuclear coverage.

75 citations

whole-genome sequencingstatistical model

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