Sophie R. Harvey

The paper develops SIDFold, a deep learning model that integrates SID-nMS data with AlphaFold to improve protein complex structure prediction accuracy.

This study investigates how ZW-1261, an FGBP-targeting inhibitor, disrupts HIV-1 capsid morphology by affecting pentameric subunits and core closure.

This paper demonstrates how electron capture charge reduction (ECCR) combined with surface induced dissociation improves the characterization of protein complex topology and glycoprotein heterogeneity.

This study successfully designs transmembrane beta-barrels from first principles, revealing structural constraints and enabling custom pore design for biotechnology applications.