William H. Press

The paper uses population dynamics models to analyze parameter regimes for adaptation versus extinction under environmental fluctuations and phenotypic diversity strategies.

The paper introduces a method to decode large DNA barcode sets with high accuracy even at high sequencing error rates using fast trimer statistics and GPU parallelism.

The paper profiles cleavage specificity and kinetics of CRISPR nucleases using NucleaSeq and CHAMP, finding engineered Cas9s show improved specificity while wtCas12a has similar specificity to wtCas9 in vitro.

The paper introduces and validates FREE barcodes, which correct DNA synthesis and sequencing errors, including insertions and deletions, improving accuracy and efficiency in high-throughput sequencing.