Jose Abelardo C. Lemos

This study investigates how glutathione import affects zinc tolerance in Streptococcus mutans, revealing a balance between protection and toxicity through a Trojan horse mechanism.

This paper characterizes EecP, a novel cell wall-anchored phosphodiesterase in E. faecalis that degrades extracellular c-di-AMP, showing its role in modulating host immune responses and infection outcomes.

This study shows that HP-29, a halogenated phenazine, inhibits Gram-positive bacteria like S. mutans and its efficacy is significantly enhanced by zinc supplementation.

This study shows that metal uptake systems are critical for Enterococcus faecalis virulence in both diabetic and non-diabetic wound infections, with differences in metal bioavailability between the two conditions.

This paper shows fructose activates a stress response in Streptococcus mutans similar to methylglyoxal and hydrogen peroxide, affecting gene expression and bacterial competitiveness.

This study identifies E. faecalis genes involved in competing with L. crispatus using transposon sequencing and RNA sequencing, revealing key pathways and proteins affecting susceptibility to L. crispatus killing.

This study identifies a novel heme-degrading enzyme in Enterococcus faecalis that enables anaerobic heme degradation, iron acquisition, and virulence.