Debra N. Brunson

This paper characterizes EecP, a novel cell wall-anchored phosphodiesterase in E. faecalis that degrades extracellular c-di-AMP, showing its role in modulating host immune responses and infection outcomes.

This study shows that metal uptake systems are critical for Enterococcus faecalis virulence in both diabetic and non-diabetic wound infections, with differences in metal bioavailability between the two conditions.

This study identifies a novel heme-degrading enzyme in Enterococcus faecalis that enables anaerobic heme degradation, iron acquisition, and virulence.