Ana Lidia Flores‐Mireles

This study identifies the Efg1 regulon active in C. albicans during growth in human urine, validates its clinical relevance in catheter samples, and characterizes key downstream factors involved in fungal CAUTI.

This paper characterizes EecP, a novel cell wall-anchored phosphodiesterase in E. faecalis that degrades extracellular c-di-AMP, showing its role in modulating host immune responses and infection outcomes.

This study shows that liquid-infused silicone catheters reduce C. auris fungal burden, systemic spread, and inflammation in bladder infections.

This study identifies loss-of-function mutations in RBA1 as a convergent adaptation in C. auris that enhances its ability to adhere, form biofilms, and cause infections.

This study demonstrates that gene therapy using rAAV9-GLDC prevents disease and death in a mouse model of non-ketotic hyperglycinemia.

This study shows that fibrin accumulation in a catheterized bladder promotes anti-inflammatory macrophage polarization, which impairs antimicrobial responses and allows bacterial persistence in UTIs.

This study identifies esrr{gamma}a's role in nephron development and ciliogenesis through prostaglandin signaling and cooperation with ppargc1a.