Apurba Sarkar

This study uses numerical simulations to show that ERM-mediated actin-membrane coupling is critical for centrosome centering and spindle geometry through interactions with microtubules and actin networks.

This study shows that multiple clustered centrosomes in antigen-presenting cells enhance T cell activation by positioning near the cell center, unlike T cells where centrosomes polarize toward the immune synapse.

This study uses a computational model to show that decentralized microtubule networks with branching and crosslinking optimize intracellular assembly processes by accelerating vesicle aggregation and spindle formation.

This study investigates how ECM-confinement affects mitotic spindle positioning and orientation through mechanical interactions and RF patterning.