Eva Kiermaier

The paper shows NLRP3 activators disrupt the AP2 complex and impair plasma membrane signaling, leading to inflammation and cell death.

The paper uses a Cellular Potts model and neural posterior estimation to infer cell migration dynamics in microfabricated environments, showing improved parameter inference over classical methods.

This study shows that multiple clustered centrosomes in antigen-presenting cells enhance T cell activation by positioning near the cell center, unlike T cells where centrosomes polarize toward the immune synapse.

The paper shows that centrosomes in non-dividing cells can fracture under mechanical stress during cell navigation, and Dyrk3 prevents this fracturing to maintain cellular function.

This study develops a fluorescent ligand to identify improved antagonists targeting the intracellular allosteric site of CCR7, showing their effectiveness in both recombinant and endogenous settings.

The paper shows that precise centriole counts are essential for B cell development but not for immune function.

The paper identifies fetal liver macrophage subpopulations and shows their role in regulating granulopoiesis and the HSC niche during embryogenesis.

This study shows that Creld2 is essential for maintaining liver metabolism homeostasis by linking the unfolded protein response (UPR) to metabolic regulation, with sex-specific effects in fatty liver disease.