Molecular BiologyScientific ReportsPeer-reviewed
Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes.
Jessel Ayra‐Plasencia, Cristina Ramos-Pérez, Silvia Santana‐Sosa…·Félix Machín
This study shows that Top2 deficiency in yeast causes a structural shift in chromosomes after replication, leading to segregation issues without triggering G2/M checkpoints.
5 citations