Félix Machín

This study shows Msc1 in yeast localizes to nucleus-vacuole junctions and excludes NPCs, maintaining NPC homeostasis during quiescence preparation.

The paper investigates the role of residual cohesin in DNA double strand break repair during late mitosis, finding that cohesin reconstitutes but is not required for homologous recombination at the MAT locus.

This study shows that the nuclear envelope protein Msc1 and the ESCRT-III complex are essential for DNA double-strand break repair during late mitosis and G2/M phases.

The paper identifies Msc1 as a nuclear envelope protein that enhances DNA repair in late mitosis by supporting homologous recombination.

This study shows that Top2 deficiency in yeast causes a structural shift in chromosomes after replication, leading to segregation issues without triggering G2/M checkpoints.

The paper identifies the Mitotic Exit Network as a protective factor against Top2 deficiency by comparing yeast strains with different Top2 alleles.