Gennaro De Libero

This study identifies PU.1 as a key transcription factor regulating epigenetic responses to Mtb, showing its role in supporting infection and potential as a therapeutic target.

The paper reanalyzes mass spectrometry data to identify two new compound classes that bind to MR1, using fragmentation filtering, molecular networking, and spectral database searching.

rCASC provides a reproducible RNA-seq analysis workflow for single-cell data, enabling functional and computational reproducibility from counts generation to cell sub-population signature identification.