Sung Jae Shin

The paper identifies that TREM2-macrophages harboring Cutibacterium acnes drive lipid metabolism changes in chronic apical periodontitis.

This study identifies a stimulatory interaction between CHI3L1 and the PD-1/PD-L1 axis in pulmonary fibrosis and shows that bispecific targeting of both reduces fibrosis in mice.

This study shows that type I interferon signaling worsens seizure severity in a mouse model and suggests targeting these signals could be a therapeutic approach for epilepsy.