Author

Suchitra Kamle

Brown UniversityORCID 0000-0001-9847-1211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Chun Geun LeeiD· 3 shared Jack Angel EliasiD· 3 shared Joyce H. LeeiD· 3 shared Takayuki SadanagaiD· 3 shared Bing MaiD· 2 shared Han-Seok JeongiD· 2 shared Sung Jae ShiniD· 2 shared Augustine M.K. ChoiiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

Chun Geun LeeORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 17, 2025

Bispecific Targeting of CHI3L1 and PD-1/PD-L1 Axis as a Novel Therapeutic Strategy for Idiopathic Pulmonary Fibrosis

Han-Seok Jeong, Takayuki Sadanaga, Joyce H. Lee…·Chun Geun Lee

This study identifies a stimulatory interaction between CHI3L1 and the PD-1/PD-L1 axis in pulmonary fibrosis and shows that bispecific targeting of both reduces fibrosis in mice.

1 citation

mouseexperimental assay

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ImmunologybioRxivPreprintMay 26, 2025

Kasugamycin inhibits melanoma lung metastasis and regulates CHI3L1-driven M2-like tumor-associated macrophage differentiation

Takayuki Sadanaga, Han-Seok Jeong, Roberto Cortez…·Chun Geun Lee

1 citation

mousehuman

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ImmunologyThe Journal of ImmunologyPeer-reviewedSep 18, 2024

Chitinase 3-like-1 (CHI3L1) Inhibits Innate Anti-Tumor and Tissue Remodeling ImmuneResponses by Regulating CD47-SIRPα and CD24-Siglec10-Mediated Phagocytosis

Bing Ma, Suchitra Kamle, Takayuki Sadanaga…·Jack Angel Elias

This study shows CHI3L1 inhibits macrophage phagocytosis by modulating CD47-SIRPα and CD24-Siglec10 pathways, contributing to immune evasion in cancer and COPD.

12 citations

humanproteomics

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