ImmunologybioRxivPreprint
Bispecific Targeting of CHI3L1 and PD-1/PD-L1 Axis as a Novel Therapeutic Strategy for Idiopathic Pulmonary Fibrosis
Han-Seok Jeong, Takayuki Sadanaga, Joyce H. Lee…·Chun Geun Lee
This study identifies a stimulatory interaction between CHI3L1 and the PD-1/PD-L1 axis in pulmonary fibrosis and shows that bispecific targeting of both reduces fibrosis in mice.
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