Molecular BiologyScience AdvancesPeer-reviewed
Distinct roles of LARP1 and 4EBP1/2 in regulating translation and stability of 5'TOP mRNAs
Tobias Hochstoeger, Panagiotis Papasaikas, Ewa Piskadlo, Jeffrey Alan Chao
This study investigates the roles of LARP1 and 4EBP1/2 in regulating translation and stability of 5'TOP mRNAs using single-molecule imaging, showing 4EBP1/2's dominant repression and LARP1's selective protection.
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