Author

Josef Redolfi

Friedrich Miescher Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Luca GiorgettiiD· 2 shared Mariya Kryzhanovska· 2 shared Sébastien A. SmallwoodiD· 2 shared Yinxiu ZhaniD· 2 shared Bas van SteenseliD· 1 shared Christ LeemansiD· 1 shared Christian Valdes· 1 shared Ewa PiskadloiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

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10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

Luca GiorgettiORCID

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2 papers

Recent·Most cited

Nonlinear control of transcription through enhancer-promoter interactions

Jessica Zuin, Grégory Roth, Yinxiu Zhan, Julie Cramard, Josef Redolfi, Ewa Piskadlo, Pia Mach, Mariya Kryzhanovska, Gergely Tihanyi, Hubertus Kohler, M Eder, Christ Leemans, Bas van Steensel, Peter Meister, Sébastien A. Smallwood, Luca Giorgetti

The paper quantifies how enhancer-promoter interactions influence transcription through nonlinear relationships and reveals mechanisms of transcriptional control via chromosome structure.

Nature · Apr 13, 2022Peer-reviewedMolecular Biology

Modeling of DNA methylation in cis reveals principles of chromatin folding in vivo in the absence of crosslinking and ligation

Josef Redolfi, Yinxiu Zhan, Christian Valdes, Mariya Kryzhanovska, Isabel Misteli Guerreiro, Vytautas Iešmantavičius, Guido Tiana, Tim Pollex, Jop Kind, Sébastien A. Smallwood, Wouter L. de Laat, Luca Giorgetti

The paper introduces damC, a method to measure chromatin structure in vivo without crosslinking or ligation, confirming TADs and CTCF loops and showing chromatin rigidity below 5 kilobases.

bioRxiv · Sep 3, 2018 · PreprintGenomics