Author

Christina F. Budden

University of BonnORCID 0000-0003-0862-0119Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alesja Dernst· 1 shared Andreas Jaensch· 1 shared Antonia Wagener· 1 shared Bianca Martin· 1 shared Eicke LatziD· 1 shared Felix MeissneriD· 1 shared Fraser Duthie· 1 shared Harald Andreas Färber· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alesja Dernst

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1 paper

Recent·Most cited

ImmunologyCell ReportsPeer-reviewedSep 1, 2024

Butyrate and propionate are microbial danger signals that activate the NLRP3-inflammasome in human macrophages in the presence of TLR stimulation

Wei Wang, Alesja Dernst, Bianca Martin…·M. S. J. Mangan

The paper shows that butyrate and propionate activate the NLRP3 inflammasome in human macrophages when combined with TLR agonists, through HDAC inhibition and epigenetic changes.

135 citationstop 1%

humanproteomics

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