Giuseppe Blasi

The paper identifies two reproducible reward imaging phenotypes linked to dopamine D2 receptor function and shows differential responses to antipsychotic drugs.

The paper introduces co-expression-based models to improve eQTL predictions and identifies novel schizophrenia-associated genes using brain RNA-seq data.

The paper links miR-137 and its target genes to schizophrenia risk through emotion processing in the prefrontal cortex, showing allele associations with brain activation patterns.

A genome-wide association study of 69,369 schizophrenia cases and 236,642 controls identifies 270 risk loci, prioritizes 130 genes, and links common and rare risk variants to neuronal synaptic biology.

The paper investigates the conservation of rare schizophrenia risk variants across diverse populations and finds consistent burden in constrained genes.

The paper identifies genetic loci associated with brainstem volumes and finds genetic overlaps with psychiatric and neurological disorders.

The paper shows working memory involves brain-wide state switching, with dopamine D1/D2 receptor expression affecting stability and state transitions, and schizophrenia linked to altered network control properties.

The paper identifies a gene co-expression module enriched for schizophrenia risk genes and shows its association with treatment response in schizophrenia patients.

The paper replicates a postmortem association of LINC01268 with violent suicide and links it to in vivo aggression and prefrontal cortex function in living individuals.

The paper shows that placental gene expression mediates the interaction between obstetrical history and genetic risk for schizophrenia, with ELCs enhancing PRS effects.