Hans‐Peter Landolt

This study uses MRS to show that thalamic brain temperature decreases during NREM sleep in humans, with deeper sleep associated with greater temperature drops.

This study tests the feasibility of delivering down-phase targeted auditory stimulation during sleep at home over seven nights, finding it technically viable and showing reduced slow-wave activity in early sleep cycles.

This study identifies a genetic variant in ADORA2A associated with alpha power in EEG and A1 adenosine receptor availability in the human brain, with sex-specific effects observed.

This study shows that caffeine intake during chronic sleep restriction reduces grey matter volume, with effects modulated by A1 adenosine receptor availability.

The paper shows that theta and alpha EEG oscillation amplitudes reflect accumulated sleep need during wakefulness, but not during the wake maintenance zone.

This study shows that regular daytime caffeine intake in men reduces REM sleep promotion and worsens sleep quality compared to placebo.

This study shows daily caffeine intake impairs working memory and reduces hippocampal activity in healthy adults, with acute withdrawal also affecting cognitive performance.

This study shows that daily caffeine intake reduces grey matter volume in humans and impairs working memory, suggesting potential long-term cognitive detriments.

The paper re-evaluates slow-wave dynamics as a proxy for NREM sleep homeostasis, finding distinct delta-wave types with different responses to sleep deprivation and recovery.

This study investigates the impact of daily caffeine intake on nighttime sleep in habitual consumers, finding no significant differences in sleep structure or quality but reduced sigma frequency EEG power density, suggesting early signs of overnight withdrawal.

This study links an AQP4 haplotype to variations in NREM slow wave energy and cognitive performance during wakefulness in humans.

This study examines how daily caffeine intake and withdrawal affect circadian rhythms and wakefulness in habitual consumers, finding no significant changes in melatonin or cortisol but increased sleepiness and attentional lapses during withdrawal.

The paper examines changes in cerebral and peripheral markers of glutamatergic signaling across the human sleep-wake cycle and finds that sleep loss increases glutamate and mGluR5 availability, which normalize with recovery sleep.