Marieke MB Hoekstra

This study uses MRS to show that thalamic brain temperature decreases during NREM sleep in humans, with deeper sleep associated with greater temperature drops.

The paper shows that presynaptic release probability, not synaptic strength, decreases with sleep loss and affects sleep need across species.

The paper identifies a novel pathway where astrocytes clear pre-synaptic autophagosomes from neurons through a cholesterol-dependent endocytosis process without requiring direct cell contact or retrograde transport.

The paper develops a model to predict brain temperature in mice based on sleep-wake state and time-of-day, finding sleep-wake sequences explain most of the variance.

The paper re-evaluates slow-wave dynamics as a proxy for NREM sleep homeostasis, finding distinct delta-wave types with different responses to sleep deprivation and recovery.

This study shows that CIRBP modulates clock gene expression and REM sleep recovery after sleep deprivation in mice.