Author

Michael Fruci

Western UniversityORCID 0000-0003-0894-9440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexei V. SavchenkoiD· 1 shared Annia Rodríguez Hernández· 1 shared Danica Galonić FujimoriiD· 1 shared Johanna M. VirtaiD· 1 shared Kaitlyn TsaiiD· 1 shared Lou Ann Verellen· 1 shared P.J. StogiosiD· 1 shared T. Skarina· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMicrobiology

Alexei V. SavchenkoORCID

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1 paper

Recent·Most cited

MicrobiologyACS Infectious DiseasesPeer-reviewedJan 30, 2026

Structural analysis of 23S rRNA methylating enzyme Cfr reveals RNA binding determinants for methylation regiospecificity and antibiotic resistance

Michael Fruci, Annia Rodríguez Hernández, T. Skarina…·P.J. Stogios

This study determines the crystal structure of Cfr, identifies key residues for methylation specificity, and links these to antibiotic resistance in pathogens.

3 citationstop 4%

experimental assayhost-pathogen & immune response

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