Danica Galonić Fujimori

This study shows NUP98::KDM5A forms condensates preferentially at H3K4me3-rich loci, driving leukemogenic gene expression through chromatin engagement.

This study shows that structural modifications of oxazolidinone antibiotics alter their preference for specific penultimate amino acids during translation inhibition.

This study determines the crystal structure of Cfr, identifies key residues for methylation specificity, and links these to antibiotic resistance in pathogens.

This study identifies an intrinsically disordered region in KDM5A that binds the nucleosome's acidic patch and DNA, enabling catalytic activity through multivalent interactions.

This study investigates how chloramphenicol and oxazolidinone antibiotics inhibit mitochondrial ribosomes, finding context-specific stalling similar to their bacterial action.

This study shows KDM5A and KDM5B regulate ERV expression and immune response by modulating KRAB-ZNF genes, with degradation of KDM5A causing rapid ERV activation.

The paper shows that BET proteins are antiviral factors against SARS-CoV-2, and the viral E protein neutralizes BET-mediated post-entry antiviral effects.