Laura Escobar

This paper integrates five vertebrate single-cell multi-omic atlases to reveal a conserved cellular blueprint and dual evolutionary constraints underlying early brain conservation across vertebrates.

This study compares the development and evolution of sensory circuits in the pallium of birds, lizards, and mammals, revealing divergent developmental trajectories but functional similarity in sensory processing.

This study shows that APOE3 and APOE4 human astrocytes differentially affect Alzheimer's disease hallmarks in chimeric mice, with APOE3 reducing and APOE4 worsening pathology.

The paper shows adult mouse SCN astrocytes respond to glucocorticoids through GR activation, influencing circadian rhythms and highlighting astrocytic roles in time-keeping.

BirthSeq isolates and analyzes cells based on their birth date across vertebrate tissues, enabling temporal studies of cell fate in development.