Author

David C. Young

Brigham and Women's HospitalORCID 0000-0003-0977-7257Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

David Branch MoodyiD· 2 shared Adriaan J. MinnaardiD· 1 shared Ana M. Xet-MulliD· 1 shared Annemieke de JongiD· 1 shared Aruna R. MenoniD· 1 shared Ashton T. BelewiD· 1 shared David M. TobiniD· 1 shared Flor Torres-JuáreziD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

David Branch MoodyORCID

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3 papers

Recent·Most cited

MicrobiologyInfection and ImmunityPeer-reviewedJul 27, 2026

Protein kinase F regulates the virulence of Mycobacterium tuberculosis

Flor Torres-Juárez, Shivangi Rastogi, David C. Young…·Volker Briken

This study shows that deleting the pknF gene in Mycobacterium tuberculosis increases its virulence in mice by enhancing production of the pro-virulence lipid PDIM and reducing host survival.

DOI 10.1128/iai.00698-25

mouseproteomics

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MicrobiologybioRxivPreprintNov 6, 2025

Mapping unsolved lipidomes accelerates lipid discovery in major bacterial pathogens

Yashodhan M. Nair, Aruna R. Menon, Zonghao Lin…·D. Branch Moody

The paper maps unknown lipids in bacterial pathogens using lipidomic methods, revealing new biosynthetic products linked to virulence.

DOI 10.1101/2025.11.06.685907

humanmouse

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Pharmacology & ToxicologybioRxivPreprintJun 26, 2025

Population Pharmacokinetics and Probability of Target Attainment Analysis of Vancomycin Following Intermittent and Continuous Infusion in Adults with Cystic Fibrosis

Manav Jain, Rachel Hudson, Zubin N. Bhakta…·Venkata Yellepeddi

This study uses population pharmacokinetics to evaluate vancomycin dosing strategies in adults with cystic fibrosis, finding optimal regimens for efficacy and safety.

1 citation

humanclinical cohort / trial

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