Author

Matthias Koch

ORCID 0000-0003-1015-1577Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Carsten HopfiD· 1 shared Dieter PetitiD· 1 shared Lucía Chávez-GutiérreziD· 1 shared Martin ZachariasiD· 1 shared Sam Lismont· 1 shared Shu-Yu CheniD· 1 shared Thomas EnzleiniD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Carsten HopfORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintSep 13, 2023

APP substrate ectodomain defines A beta length by restraining gamma-secretase processivity and facilitating product release

Matthias Koch, Thomas Enzlein, Shu-Yu Chen…·Lucía Chávez-Gutiérrez

The paper investigates how the APP ectodomain regulates gamma-secretase processivity and A beta peptide length, identifying it as a target for Alzheimer's disease therapies.

DOI 10.1101/2023.09.13.557360

humanproteomics

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