Author

Nicolas J. Blobel

Rockefeller UniversityORCID 0000-0003-1027-3988Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:proteomics· 1

Frequent Co-Authors

Agata SmogorzewskaiD· 2 shared Brooke A. ContiiD· 1 shared Cayla BrotoniD· 1 shared Francis P. LachiD· 1 shared Marian Okondo· 1 shared Molly C. Kottemann· 1 shared Nanda Kumar SasiiD· 1 shared Penelope D. RuiziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCell Biology

Agata SmogorzewskaORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintNov 13, 2025

Genotoxic formaldehyde and lipid aldehydes are sources of DNA damage in keratinocytes

Nicolas J. Blobel, Yibing Yao, Marian Okondo, Agata Smogorzewska

This study identifies ADH5 and ALDH3-family enzymes as critical for detoxifying endogenous aldehydes in FA-deficient keratinocytes, preventing DNA damage and carcinogenesis.

1 citation

humanDNA methylation

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Molecular BiologyNature CommunicationsPeer-reviewedMar 2, 2024

RTF2 controls replication repriming and ribonucleotide excision at the replisome

Brooke A. Conti, Penelope D. Ruiz, Cayla Broton…·Agata Smogorzewska

This study shows RTF2 regulates replication repriming and ribonucleotide excision at the replisome, ensuring efficient replication restart and preventing replication stress.

8 citations

humanDNA methylation

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