Author
Mario Negri Institute for Pharmacological ResearchORCID 0000-0003-1055-1271Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Serena Scozzari, Stefano Fabrizio Columbro, Monica Favagrossa…·Valentina Bonetto
This study investigates the effects of HDAC inhibition and its combination with arimoclomol on TDP-43 proteinopathy in vitro and in vivo, finding delayed pathology and synergistic neuroprotection.
Giulia D’Arrigo, Giulia Cutugno, Maria Teresa Golia…·Claudia Verderio
This study shows that microglial extracellular vesicles deliver C1q to presynaptic sites, promoting synaptic pruning and linking vesicle release to synaptic remodeling.
Ganesh Parameshwar Bhat, Santo Diprima, Cristian G. Beccaría…·Dario Bonanomi
The paper identifies early endothelial activation at the blood-nerve barrier as a key feature of ALS, occurring before CNS vascular changes and motor neuron damage.
Erik Nutma, Nurun Nahar Fancy, Maria Weinert…·David R. Owen
The paper shows TSPO expression increases in activated microglia in rodent models but not in human neurodegenerative diseases, indicating species-specific differences in TSPO function.