Fumio Matsuda

The paper develops MassBank Human, a curated metabolomics resource that improves structural annotation of the human metabolome, doubling coverage in colorectal cancer cells and identifying acetylated polyamines as metabolic markers.

This study shows that in nitrogen-starved Lipomyces starkeyi cells, lipid droplet expansion is linked to the TCA cycle and pentose phosphate pathway, with citric acid and NADPH facilitating fatty acid synthesis and energy storage.

The paper constructs a combinatorial repression library in E. coli to optimize flux distribution for mevalonate production by modifying ribosome-binding sites of key genes.

This study compares aerobic glycolysis in cancer cells and yeast under mitochondrial stress, finding conserved metabolic rewiring and ATP transport mechanisms that support cell survival.

This study introduces two methods to control false discovery rate in non-targeted metabolomics by improving compound search reliability and enabling novel metabolite identification.