Author

Sachin Mishra

National Centre for Biological SciencesORCID 0000-0003-1095-9920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Dimple NotaniiD· 3 shared Anchala PandeyiD· 1 shared Anurag Kumar SinghiD· 1 shared Arif Hussain Najar· 1 shared Awadhesh PanditiD· 1 shared Bhagyashree Shelar· 1 shared Darshan SreenivasiD· 1 shared Deepak PantiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Dimple NotaniORCID

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3 papers

Recent·Most cited

Molecular BiologyCell ReportsPeer-reviewedFeb 1, 2025

Hypoxia-induced CTCF mediates alternative splicing via coupling chromatin looping and RNA Pol II pause to promote EMT in breast cancer

Parik Kakani, Shruti Ganesh Dhamdhere, Deepak Pant…·Sanjeev Shukla

This study shows hypoxia-induced CTCF promotes EMT in breast cancer by regulating alternative splicing through chromatin looping and RNA Pol II pausing.

12 citations

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintMay 20, 2024

Compaction of Active Chromatin Domains and Promoters by H3S10 Phosphorylation during Mitosis Preserves Interphase-Specific Chromatin Structure and Function

Sweety Meel, Sachin Mishra, Rajat Mann…·Dimple Notani

This study shows that H3S10 phosphorylation during mitosis preserves chromatin domain and promoter identity by compacting active regions and stabilizing nucleosomes, ensuring proper transcriptional reactivation in the next interphase.

2 citations

ChIP-seqDNA methylation

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GenomicsbioRxivPreprintMar 14, 2023

Genomic surveillance reveals circulation of multiple variants and lineages of SARS-CoV-2 during COVID-19 pandemic in Indian city of Bengaluru

Darshan Sreenivas, Vinay Kumar, Kathirvel Kandasamy…·Dimple Notani

The paper reports genomic surveillance of SARS-CoV-2 in Bengaluru, India, across three pandemic waves, identifying 18 clades and 196 lineages, with Delta dominant in the second wave and Omicron BA.2 dominant in the third.

6 citations

viruswhole-genome sequencing

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