Compaction of Active Chromatin Domains and Promoters by H3S10 Phosphorylation during Mitosis Preserves Interphase-Specific Chromatin Structure and Function
Sweety Meel, Sachin Mishra, Rajat Mann, Arif Hussain Najar, Anurag Kumar Singh, Dimple Notani
This study shows that H3S10 phosphorylation during mitosis preserves chromatin domain and promoter identity by compacting active regions and stabilizing nucleosomes, ensuring proper transcriptional reactivation in the next interphase.
bioRxiv · May 20, 2024 · PreprintMolecular Biology