Anurag Kumar Singh

The paper examines how transcription factor co-occupancy and chromatin structure influence somatic mutation rates in liver cancer regulatory regions.

This study shows that H3S10 phosphorylation during mitosis preserves chromatin domain and promoter identity by compacting active regions and stabilizing nucleosomes, ensuring proper transcriptional reactivation in the next interphase.

This study examines how HPV integration affects host chromatin structure and gene regulation in cervical cancer, finding that integrations are enriched in active chromatin regions and induce local and long-range transcriptional upregulation within TADs.

The paper shows boundary-associated RNAs enhance TAD insulation by promoting CTCF clustering at TAD boundaries.

The paper shows that unliganded ERα pre-marks enhancer sites, which form 3D clusters upon ligand exposure, driving transient gene expression.