The paper identifies sex-biased genes and eQTL across the human genome, showing their association with autoimmune diseases and sex differences in gene regulation.

Human Molecular Genetics · Jan 1, 2026Peer-reviewedGenetic & Genomic Medicine

SMARCA2 is an essential and potent cofactor for a specific subset of the glucocorticoid response in A549 cells

Schuyler M. Melore, D. Dewran Koçak, Keith Siklenka, Graham D. Johnson, Courtney A. Williams, Luke C. Bartelt, Angela G. Jones, Alejandro Barrera, Revathy Venukuttan, Charles A. Gersbach, Timothy E. Reddy

The paper identifies SMARCA2 as a critical cofactor for a subset of glucocorticoid response genes in A549 cells through a CRISPR screen and functional analysis.

bioRxiv · Nov 13, 2025 · PreprintGenomics

Context-specific eQTLs reveal causal genes underlying shared genetic architecture of critically ill COVID-19 and idiopathic pulmonary fibrosis

Trisha Dalapati, Liuyang Wang, Angela G. Jones, Jonathan Cardwell, Iain R. Konigsberg, Yohan Bossé, Don D. Sin, Wim Timens, Ke Hao, Ivana V. Yang, Dennis C. Ko

The paper identifies shared genetic variants between critically ill COVID-19 and idiopathic pulmonary fibrosis by integrating GWAS with context-specific eQTLs and transcriptomics.

medRxiv · Jul 13, 2024 · PreprintGenetic & Genomic Medicine

A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression

Margaret R. Gaggioli, Angela G. Jones, Ioanna Panagi, E. Washington, Rachel E. Loney, Janina H. Muench, Richard G. Brennan, Teresa L. M. Thurston, Dennis C. Ko

bioRxiv · Feb 14, 2024 · PreprintMolecular Biology