Author

A. Chaikuad

Goethe University FrankfurtORCID 0000-0003-1120-2209Unclaimed ORCID profile · follow to get notified of new preprints

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A. Chaikuad12 papers

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alex N. BullockiD· 1 shared Allison S. LimpertiD· 1 shared Betsaida Bibo‐Verdugo· 1 shared Chancievan ThangaratnarajahiD· 1 shared Dhanya R. Panickar· 1 shared Douglas J. SheffleriD· 1 shared F. von DelftiD· 1 shared Fabiana Izidro LayngiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Alex N. BullockORCID

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2 papers

Recent·Most cited

Cancer BiologyACS Chemical BiologyPeer-reviewedFeb 12, 2026

Synthesis and Characterization of ULK1/2 Kinase Inhibitors that Inhibit Autophagy and Upregulate Expression of Major Histocompatibility Complex I for the Treatment of Non-Small Cell Lung Cancer

Fabiana Izidro Layng, Huiyu Ren, Nicole A. Bakas…·Nicholas D. P. Cosford

The paper reports the design, synthesis, and characterization of new ULK1/2 inhibitors that inhibit autophagy and upregulate MHC I in NSCLC cells, supporting their potential as cancer therapeutics.

3 citationstop 3%

humanexperimental assay

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Molecular BiologyScientific ReportsPeer-reviewedDec 4, 2019

Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension

A. Chaikuad, Chancievan Thangaratnarajah, F. von Delft, Alex N. Bullock

The paper determines the crystal structure of the BMPR2 kinase domain and analyzes how disease-associated mutations affect its stability and potential for therapeutic intervention.

18 citations

humanexperimental assay

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