Author

Nikita Markov

University of BernORCID 0000-0003-1121-973XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Carole BourquiniD· 2 shared Anna I. BrichkinaiD· 1 shared Aref HosseiniiD· 1 shared Aurélien PommieriD· 1 shared Csaba SzabóiD· 1 shared Darko StojkoviD· 1 shared Eloïse DupuychaffrayiD· 1 shared Hans‐Uwe SimoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Carole BourquinORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyRedox BiologyPeer-reviewedAug 28, 2026

Inhibition of 3-mercaptopyruvate sulfurtransferase enhances CD8⁺ T-cell antitumor immunity

Muriel Urwyler, Marietta Margaréta Korsós, Eloïse Dupuychaffray…·Carole Bourquin

This study shows that inhibiting 3-MST reduces H2S in renal cell carcinoma, enhances T cell activation, and boosts antitumor immunity.

DOI 10.1016/j.redox.2026.104373

humanbulk RNA-seq

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ImmunologybioRxivPreprintNov 1, 2025

Mitochondrial Dysfunction Rewires Macrophage Metabolism, Driving Pro-inflammatory Priming and Immune System Remodeling

Nikita Markov, Aref Hosseini, Timothée Fettrelet…·Hans‐Uwe Simon

This study shows mitochondrial dysfunction in macrophages drives a pro-inflammatory metabolic shift, impairing M2 traits and promoting M1-like activation, with systemic immune consequences.

1 citation

mouseproteomics

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