Carole Bourquin

This study shows that inhibiting 3-MST reduces H2S in renal cell carcinoma, enhances T cell activation, and boosts antitumor immunity.

This study shows mitochondrial dysfunction in macrophages drives a pro-inflammatory metabolic shift, impairing M2 traits and promoting M1-like activation, with systemic immune consequences.

This study shows that inhibiting the ZnF-UBP domain of HDAC6 in multiple myeloma cells reduces proliferation and aggresome formation, suggesting it as a therapeutic target.

This study identifies 11beta-HSD1 as a driver of myofibroblast differentiation in CKD, showing its inhibition reduces fibrosis and improves renal function.