Author

Pablo Hofbauer

Institute of Molecular Biotechnology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Maria NovatchkovaiD· 3 shared Sasha MendjaniD· 3 shared Alison DeyettiD· 2 shared Clara Schmidt· 2 shared Katherina TaverniniiD· 2 shared Lavinia Ceci GinistrelliiD· 2 shared Nóra Pápai· 2 shared Stefan M. JahneliD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersDevelopmental Biology

Maria NovatchkovaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multi-chamber cardioids unravel human heart development and cardiac defects

Clara Schmidt, Alison Deyett, Tobias Ilmer, Simon Haendeler, Aranxa Torres-Caballero, Maria Novatchkova, Michael A. Netzer, Lavinia Ceci Ginistrelli, Estela Mancheño Juncosa, T. K. Bhattacharya, Amra Mujadzic, Lokesh G. Pimpale, Stefan M. Jahnel, Martina Cirigliano, Daniel Reumann, , Sasha Mendjan

This paper develops a multi-chamber cardioid platform to study human heart development and defects by generating compartment-specific gene expression, morphology, and function.

Cell · Nov 28, 2023Peer-reviewedDevelopmental Biology

ZFP462 targets heterochromatin to transposon-derived enhancers restricting transcription factor binding and expression of lineage-specifying genes

Ramesh Yelagandula, Karin Stecher, Maria Novatchkova, Luca Michetti, Georg Michlits, Jingkui Wang, Pablo Hofbauer, Carina Pribitzer, Gintautas Vainorius, Luke Isbel, Sasha Mendjan, Dirk Schübeler, Ulrich Elling, Julius Brennecke, Oliver Bell

This study identifies ZFP462's role in restricting endodermal gene expression by targeting transposon-derived enhancers and modulating histone methylation in mouse embryonic stem cells.

bioRxiv · Jun 28, 2021 · PreprintGenetics

Cardioids reveal self-organizing principles of human cardiogenesis

Pablo Hofbauer, Stefan M. Jahnel, Nóra Pápai, Magdalena Giesshammer, Alison Deyett, Clara Schmidt, Mirjam Penc, Katherina Tavernini, Nastasja Grdseloff, Christy Meledeth, Lavinia Ceci Ginistrelli, Claudia Ctortecka, Šejla Šalic, Maria Novatchkova, Sasha Mendjan

This paper establishes self-organizing cardioids from human pluripotent stem cells that form chamber-like structures and identifies signaling pathways governing their development.

Cell · May 20, 2021Peer-reviewedDevelopmental Biology